Tesamorelin

Description

Tesamorelin is a synthetic analogue of the full 44-residue growth hormone-releasing hormone, modified with a trans-3-hexenoyl group attached to the N-terminal tyrosine. That acyl cap is what protects it from rapid DPP-4 cleavage, giving it much better stability in solution than native GHRH.

Product Specifications

• Compound: Tesamorelin
• Class: Synthetic 44-amino-acid GHRH analogue
• Sequence: Human GHRH(1-44) with a trans-3-hexenoyl group at the N-terminus
• Molecular weight: ~5136 Da
• CAS number: 218949-48-5
• Form: Lyophilised powder in a sealed glass vial
• Available sizes: 10 mg per vial
• Purity: ≥99% by HPLC — see the certificate of analysis for the batch supplied

Research Background

Tesamorelin appears in GHRH receptor and peptide stability research. Topics include:

• GHRH receptor activation assays
• N-terminal acylation as a DPP-4 protection strategy
• Comparative stability against sermorelin and native GHRH
• Somatotroph cell model systems

Peer-reviewed literature on this compound can be searched through PubMed and the NIH PMC database. Troy Peptides supplies reference material only and does not provide research protocols or interpret published findings.

Analytical Verification

Identity and purity are confirmed by independent third-party analysis before release.

• High-performance liquid chromatography (HPLC) for purity quantification
• Mass spectrometry (MS) for identity and molecular weight confirmation

A third-party certificate of analysis is available for every product. See Certificates of Analysis.

Handling and Storage

• Lyophilised material: store cool, dry and away from direct light; −20 °C for long-term storage
• After reconstitution: refrigerate at 2–8 °C and protect from light
• Avoid repeated freeze–thaw cycles

Terms of Sale

This product is supplied strictly for in vitro laboratory research. It is not a drug, food or cosmetic, has not been evaluated by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. By purchasing, the buyer confirms that they are at least 21 years of age and a qualified research professional or institution, and that this material will not be used for human consumption, veterinary use or any in vivo application.