Description
PT-141 is a cyclic seven-residue melanocortin agonist and the deaminated metabolite of Melanotan II, differing from it by a free C-terminal carboxylic acid in place of the amide. That single change shifts its receptor selectivity, which is why the two are so often compared side by side.
Product Specifications
- Compound: PT-141 (bremelanotide)
- Class: Cyclic lactam heptapeptide melanocortin agonist
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Molecular weight: ~1025 Da
- CAS number: 189691-06-3
- Form: Lyophilised powder in a sealed glass vial
- Available sizes: 10 mg per vial
- Purity: ≥99% by HPLC — see the certificate of analysis for the batch supplied
Research Background
PT-141 is used as a reference agonist in melanocortin receptor research. Topics include:
- MC3R and MC4R selectivity profiling
- Comparative pharmacology against Melanotan II
- Cyclic peptide conformational analysis
- Receptor signalling bias studies
Peer-reviewed literature on this compound can be searched through PubMed and the NIH PMC database. Troy Peptides supplies reference material only and does not provide research protocols or interpret published findings.
Analytical Verification
Identity and purity are confirmed by independent third-party analysis before release.
- High-performance liquid chromatography (HPLC) for purity quantification
- Mass spectrometry (MS) for identity and molecular weight confirmation
A third-party certificate of analysis is available for every product. See Certificates of Analysis.
Handling and Storage
- Lyophilised material: store cool, dry and away from direct light; −20 °C for long-term storage
- After reconstitution: refrigerate at 2–8 °C and protect from light
- Avoid repeated freeze–thaw cycles
Terms of Sale
This product is supplied strictly for in vitro laboratory research. It is not a drug, food or cosmetic, has not been evaluated by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. By purchasing, the buyer confirms that they are at least 21 years of age and a qualified research professional or institution, and that this material will not be used for human consumption, veterinary use or any in vivo application.
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