Description
Melanotan II is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone. The lactam bridge locks the peptide into a constrained ring, which greatly increases its stability and receptor affinity relative to the linear native hormone.
Product Specifications
- Compound: Melanotan II (MT-2)
- Class: Cyclic lactam heptapeptide analogue of alpha-MSH
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
- Molecular weight: ~1024 Da
- CAS number: 121062-08-6
- Form: Lyophilised powder in a sealed glass vial
- Available sizes: 10 mg per vial
- Purity: ≥99% by HPLC — see the certificate of analysis for the batch supplied
Research Background
Melanotan II is used as a reference agonist in melanocortin receptor research. Topics include:
- Binding profiles across MC1R, MC3R, MC4R and MC5R
- Cyclic constraint and structure-activity relationship studies
- Melanogenesis assays in cultured melanocytes
- Comparative pharmacology against linear alpha-MSH
Peer-reviewed literature on this compound can be searched through PubMed and the NIH PMC database. Troy Peptides supplies reference material only and does not provide research protocols or interpret published findings.
Analytical Verification
Identity and purity are confirmed by independent third-party analysis before release.
- High-performance liquid chromatography (HPLC) for purity quantification
- Mass spectrometry (MS) for identity and molecular weight confirmation
A third-party certificate of analysis is available for every product. See Certificates of Analysis.
Handling and Storage
- Lyophilised material: store cool, dry and away from direct light; −20 °C for long-term storage
- After reconstitution: refrigerate at 2–8 °C and protect from light
- Avoid repeated freeze–thaw cycles
Terms of Sale
This product is supplied strictly for in vitro laboratory research. It is not a drug, food or cosmetic, has not been evaluated by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. By purchasing, the buyer confirms that they are at least 21 years of age and a qualified research professional or institution, and that this material will not be used for human consumption, veterinary use or any in vivo application.
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