TB-500

Description

TB-500 is a synthetic, N-acetylated seven-residue peptide corresponding to the actin-binding region of thymosin beta-4. Because it reproduces the active fragment rather than the full 43-residue protein, it is far easier to synthesise and handle, and it appears frequently in cytoskeletal research.

Product Specifications

• Compound: TB-500 (thymosin beta-4 fragment 17-23)
• Class: Synthetic acetylated heptapeptide
• Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
• Molecular weight: ~889 Da
• CAS number: 885340-08-9
• Form: Lyophilised powder in a sealed glass vial
• Available sizes: 5 mg per vial
• Purity: ≥99% by HPLC — see the certificate of analysis for the batch supplied

Research Background

TB-500 is studied primarily in relation to actin dynamics. Research topics include:

• G-actin sequestration and cytoskeletal assembly studies
• Cell motility and migration assays
• Comparative work against full-length thymosin beta-4
• Endothelial cell model systems

Peer-reviewed literature on this compound can be searched through PubMed and the NIH PMC database. Troy Peptides supplies reference material only and does not provide research protocols or interpret published findings.

Analytical Verification

Identity and purity are confirmed by independent third-party analysis before release.

• High-performance liquid chromatography (HPLC) for purity quantification
• Mass spectrometry (MS) for identity and molecular weight confirmation

A third-party certificate of analysis is available for every product. See Certificates of Analysis.

Handling and Storage

• Lyophilised material: store cool, dry and away from direct light; −20 °C for long-term storage
• After reconstitution: refrigerate at 2–8 °C and protect from light
• Avoid repeated freeze–thaw cycles

Terms of Sale

This product is supplied strictly for in vitro laboratory research. It is not a drug, food or cosmetic, has not been evaluated by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. By purchasing, the buyer confirms that they are at least 21 years of age and a qualified research professional or institution, and that this material will not be used for human consumption, veterinary use or any in vivo application.